Vicriviroc and Peripheral Neuropathy: Results from AIDS Clinical Trials Group 5211
نویسندگان
چکیده
منابع مشابه
Peripheral neuropathy in ANCA-associated vasculitis: outcomes from the European Vasculitis Study Group trials.
OBJECTIVES To describe the incidence and prevalence of peripheral neuropathy in ANCA-associated vasculitis (AAV); to evaluate the correlation of neuropathy with other clinical manifestations; and to review the long-term outcome of treated neuropathy. METHODS Presence of neuropathy was determined using items from the BVAS and vasculitis damage index (VDI) during 5 years from enrollment into cl...
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گزارشهای سازمان استاندارد ملی در آمریکا از سال ۱۹۵۳ بیانگر کاهش درصد مرگ و میر ناشی از سل و ابتلا به آن بوده است. حتی در اواخر ۱۹۷۰ با افزایش مهاجرت از کامبوج، لائوس و ویتنام به سایر نقاط جهان کاهش درصد ابتلا به سل نشان داده شده است. در طی سالهای ۸۷- ۱۹۸۵ افزایش موارد ابتلا به سل در سیاه پوستان /۶ ٪۳ در اسپانیائیها ۱۲/۷ ٪و در سفید پوستان غیر اسپانیایی ٪۴ / ۸ تخمین زده شده است. از سال ۱۹۹۰ اپید...
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The 24-week extension of AIDS Clinical Trials Group Protocol 359, a study of human immunodeficiency virus (HIV)-infected, indinavir-experienced patients, was designed to study the durability of "salvage" treatment regimens. Patients received saquinavir in combination with either ritonavir or nelfinavir and, in addition, delavirdine, adefovir, or both. Patients who demonstrated a virologic respo...
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The enhanced-sensitivity Trofile assay (Monogram Biosciences) was used to retest coreceptor use at both study screening and study entry for 118 treatment-experienced subjects in AIDS Clinical Trials Group A5211 who had CCR5-tropic (R5) virus detected by the original Trofile assay at study screening. Among 90 recipients of vicriviroc, a significantly (P< .001) greater mean reduction in HIV-1 RNA...
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N europathies are among the commonest of long-term diabetes complications, and the management of chronic sensorimotor distal symmetric polyneuropathy (DPN) presents a significant therapeutic challenge (1,2). DPN may manifest with several diverse clinical presentations, including troublesome, neuropathic pain and, at the other end of the spectrum, the insensitive foot at risk of ulceration. Wher...
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ژورنال
عنوان ژورنال: HIV Clinical Trials
سال: 2010
ISSN: 1528-4336,1945-5771
DOI: 10.1310/hct1101-51